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Home⇒ Medical Science⇒ Biotechnology⇒ Monoclonal antibodies
1-Dont try to cram or spend more time here just read it fast and cover syllabus then practice MCQ's cheptor of same topic to check your progress. . |
2-Wrong options are also given but dont concentrate there, Right answer is in bold format. |
Q1 ⇒ The cross linkage of antigens by antibodies is known as agglutination [other wrong options] [Discuss in forum] complement fixation a cross reaction all of these |
Q2 ⇒ Helper T cells assist in the functions of certain B cells and other T cells [other wrong options] [Discuss in forum] certain B cells certain T cells none of the above |
Q3 ⇒ TC cells are important in controlling all of these [other wrong options] [Discuss in forum] virus infections allergy autoimmunity |
Q4 ⇒ T cells are the source of all of these [other wrong options] [Discuss in forum] interleukin interferon lymphotoxin |
Q5 ⇒ A cytokine that stimulates the activity of B and T cells is interlukin-2 [other wrong options] [Discuss in forum] lymphotoxin interlukin-1 all of these |
Q6 ⇒ In human B cells and T cells are matured in the bone marrow and thymus respectively [other wrong options] [Discuss in forum] lymph nodes and spleen respectively bursa and thymus respectively none of these |
Q7 ⇒ Which of the following is incorrect? MAbs can not be used in such non-infectious diseases as those of endocrine system [other wrong options] [Discuss in forum] MAbs can be used to diagnose or treat diseases MAbs can be used in tumor scanning MAbs canbe used in cancer diagnosis |
Q8 ⇒ Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the absence of human immune response against murine proteins (HAMA) response [other wrong options] [Discuss in forum] presence of HAMA response poor recognition of immunoglobulin, Ig constant regions all of the above |
Q9 ⇒ The EBV-hybridoma technique all of the above [other wrong options] [Discuss in forum] immortalizes the donor Bcells facilitates the proliferation of antigen specific B cells gives much higher hybridization frequencies |
Q10 ⇒ The hybrid cells can be propagated both (a) and (b) [other wrong options] [Discuss in forum] in tissue culture as ascites in peritoneal cavity of mice none of these |
Q11 ⇒ The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as all of these [other wrong options] [Discuss in forum] transformation of antigen specific B lymphocytes (EBV) hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes combination of EB Vand hybridoma techniques |
Q12 ⇒ It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at high frequencies [other wrong options] [Discuss in forum] moderate frequencies low frequencies at no frequency |
Q13 ⇒ Which of the following is correct? rabbits do not make myelomas whereas mice are unable to synthesize antibodies [other wrong options] [Discuss in forum] rabbits do not make myelomas whereas mice are able to synthesize antibodies rabbits make myelomas whereas mice are unable to synthesize antibodies rabbits make myelomas whereas mice are able to synthesize antibodies |
Q14 ⇒ An example of mosaic antigen is virus [other wrong options] [Discuss in forum] bacteria a hapten protein |
Q15 ⇒ The antigen-specific lymphocytes can be immortalized by which of the following method? All of the above [other wrong options] [Discuss in forum] Transfection with tumor derived DNA Hybridization with a suitable lymphoid tumor cell Transformation following infection by Epstein-Barr virus (EB V) |
Q16 ⇒ In monoclonal antibody technology, tumor cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a hybridoma [other wrong options] [Discuss in forum] myeloma natural killer cell lymphoblast |
Q17 ⇒ In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc., T8 cells are greatly reduced [other wrong options] [Discuss in forum] T8 cells are greatly increased T4 cells are greatly reduced T4 cells are greatly increased |
Q18 ⇒ Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with Ig MAbs [other wrong options] [Discuss in forum] IgG IgA IgE |
Q19 ⇒ Small simple molecules are poor antigens [other wrong options] [Discuss in forum] rich antigens moderate antigens heterophilic antigens |
Q20 ⇒ The Ig locus is about 2/3rd of all hybridomas [other wrong options] [Discuss in forum] l/3rd of all hybridomas l/2nd of all hybridomas 1/4th of all hybridomas |
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