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Bisphosphoglycerate (BPG) cannot bind to the oxygenated R state of hemoglobin because | |
A. | it is displaced from the heme by oxygen [Wrong Answer] |
B. | it is displaced from the heme by movement of the proximal histidine [Wrong Answer] |
C. | its binding pocket becomes too small to accommodate BPG [Correct Answer] |
D. | BPG binds to the R state with the same affinity as the T state [Wrong Answer] |