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Home⇒ Medical Science⇒ Microbiology⇒ Dna sequencing mutation and repair
1-Dont try to cram or spend more time here just read it fast and cover syllabus then practice MCQ's cheptor of same topic to check your progress. . |
2-Wrong options are also given but dont concentrate there, Right answer is in bold format. |
Q1 ⇒ Genetic variations are stable [other wrong options] [Discuss in forum] temporary influenced by the environment not heritable |
Q2 ⇒ A nonsense mutation may result into a premature termination of the synthesis of a polypeptide [other wrong options] [Discuss in forum] an abnormal elongation of a polypeptide a large deletion within the reading frame of a gene modification of mRNA |
Q3 ⇒ The promoter on an expression vector used to overproduce proteins in bacteria is a bacterial promoter [other wrong options] [Discuss in forum] expressed both in bacteria and mammalian cells not a regulated promoter the natural promoter of the gene being cloned |
Q4 ⇒ The whole-genome shotgun sequencing approach depends primarily on rapidly sequencing thousands of small randomly cloned fragments [other wrong options] [Discuss in forum] methodical sequencing a few large cloned fragments of DNA sequencing the bacterial chromosome while it is still intact all of the above |
Q5 ⇒ The DNA sequences of rRNA genes can be used to obtain a tentative identification of a new microorganism [other wrong options] [Discuss in forum] assess relatedness of eukaryotes but not prokaryotes predict the pulsed field gel pattern of a microorganism predict whether a bacteria will be gram-positive or gram-negative |
Q6 ⇒ Which of the following bacterial genome was sequenced first? H. influenzae [other wrong options] [Discuss in forum] E. coli S. pneumoniae S. thermophilus |
Q7 ⇒ Thymine dimers are directly repaired with the help of visible light by process known as photoreactivation [other wrong options] [Discuss in forum] phosphorylation excision repair photosynthesis |
Q8 ⇒ Which of the following mutations arise without exposure to external agents? Spontaneous mutations [other wrong options] [Discuss in forum] Analogous mutations Induced mutations None of these |
Q9 ⇒ Which of these mechanisms for thymine dimers repair lead to mutations? SOS repair [other wrong options] [Discuss in forum] Excision repair Photoreactivation Never leads to mutation |
Q10 ⇒ Which of the following(s) is/are steps in excision repair mechanisms? All of these [other wrong options] [Discuss in forum] Excision Incision Ligation |
Q11 ⇒ A mutagen is defined as a chemical or physical agent that induces mutations [other wrong options] [Discuss in forum] an enzyme that repairs mutations an inhibitor of gene modification a molecule which stabilizes DNA thus prevents mutations from occurring |
Q12 ⇒ The mutation which will not affect the length of a protein is, missense mutation [other wrong options] [Discuss in forum] nonsense mutation frameshift mutation all of these |
Q13 ⇒ Which of the following mutation affects only a single nucleotide? Point mutation [other wrong options] [Discuss in forum] Aerial mutation Site mutation Regional mutation |
Q14 ⇒ Differentiation of four different bases in automated sequencing systems is that each base has distinctive fluorescent tag [other wrong options] [Discuss in forum] different radioactive tag cytosine at start unique antibody bound to it |
Q15 ⇒ Changes in which of the following characterizes mutations? Both (a) and (b) [other wrong options] [Discuss in forum] Phenotype Genotype None of these |
Q16 ⇒ When mutations involve vital functions so that the mutants are nonviable, it is a lethal mutation [other wrong options] [Discuss in forum] nonsense mutation transversion none of these |
Q17 ⇒ Due to which of the following DNA repair mechanisms, one is able to distinguish newly synthesized DNA strands from older one? Old strands are methylated while new strands are not [other wrong options] [Discuss in forum] New strands do not contain cytosine bases New strands are lower in molecular size New strands are methylated while old strands are not |
Q18 ⇒ Frame shift mutation may occur as a result of none of the above [other wrong options] [Discuss in forum] formation of a thymine-dimer deamination of cytosine to uracil conversion of guanine to xanthine |
Q19 ⇒ What was the first eukaryotic chromosome to be sequenced? Yeast chromosome III [other wrong options] [Discuss in forum] Yeast chromosome XI Arabidopsis chromosome IV None of these |
Q20 ⇒ A nonsense mutation introduced into the DNA sequence of a gene may shorten the length of the protein encoded by the gene [other wrong options] [Discuss in forum] cause premature termination of the mRNA have no effect on the transcript or protein made cause a shift in reading frame |