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Home⇒ Medical Science⇒ Biochemistry⇒ Enzymes
1-Dont try to cram or spend more time here just read it fast and cover syllabus then practice MCQ's cheptor of same topic to check your progress. . |
2-Wrong options are also given but dont concentrate there, Right answer is in bold format. |
Q1 ⇒ Enzyme-driven metabolic pathways can be made more efficient by All of the above [other wrong options] [Discuss in forum] ![]() ![]() concentrating enzymes within specific cellular compartments grouping enzymes into free-floating, multienzyme complexes fixing enzymes into membranes so that they are adjacent to each other |
Q2 ⇒ The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about 58 kJ/mol [other wrong options] [Discuss in forum] ![]() ![]() 40 kJ/mol 49 kJ/mol 88 kJ/mol |
Q3 ⇒ Common feature in all serine proteases is a single reactive serine residue [other wrong options] [Discuss in forum] ![]() ![]() hydrophobic specificity pocket hydrophilic specificity pocket cluster of reactive serine residues |
Q4 ⇒ Tryprotophan synthetase of E.coli, a typical bifunctional oligomeric enzyme consist of two proteins designated A and B [other wrong options] [Discuss in forum] ![]() ![]() a protein designated A a protein A and one-subunit a a protein designated B |
Q5 ⇒ Which of the common features are shared between serine and aspartate proteases? All of the above [other wrong options] [Discuss in forum] ![]() ![]() Both require water to complete the catalytic cycle Both use a base to activate the nucleophile Both show specificity for certain amino acid sequences |
Q6 ⇒ The role of Asp 102 and His 57 during trypsin catalysis is to function as a proton shuttle [other wrong options] [Discuss in forum] ![]() ![]() neutralize the charge on the other's side chain keep the specificity pocket open clamp the substrate into the active site |
Q7 ⇒ What is the specificity of the Clostripain protease? It cleave after Arg residues [other wrong options] [Discuss in forum] ![]() ![]() It cleave after His residues It cleave after Lys residues None of the above |
Q8 ⇒ Before they can react, many molecules need to be destabilized. This state is typically achieved through the input of a small amount of activation energy [other wrong options] [Discuss in forum] ![]() ![]() changing the three-dimensional shape of the molecule oxidizing the molecules by removing electrons changing the reaction from a biosynthetic to a catabolic pathway |
Q9 ⇒ In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)---> A and B will still be produced, but not C or D [other wrong options] [Discuss in forum] ![]() ![]() A, B, C, and D will all still be produced A, B, and C will still be produced, but not D A will still be produced, but not B, C, or D |
Q10 ⇒ Which of the following statements about enzymes or their function is true? All of the above [other wrong options] [Discuss in forum] ![]() ![]() Enzymes do not alter the overall change in free energy for a reaction Enzymes are proteins whose three-dimensional form is key to their function Enzymes speed up reactions by lowering activation energy |
Q11 ⇒ The E.coli pyruvic acid dehydrogenase complex is reported to Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2 [other wrong options] [Discuss in forum] ![]() ![]() decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2 retard the reduction of pyruvic acid to acetyl Co A and CO2 Catalyze the reduction of pyruvic acid to acetyl Co A and CO2 |
Q12 ⇒ Which of the following (s) is/are serine proteases? all of these [other wrong options] [Discuss in forum] ![]() ![]() Chymotrypsin Trypsin Elastase |
Q13 ⇒ Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both forms an acyl-enzyme intermediate [other wrong options] [Discuss in forum] ![]() ![]() Both use nucleophilic attack to hydrolyze the peptide bond Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences |
Q14 ⇒ How is the enzyme COX-1 important in human health? It catalyzes the production of hormones that maintain the stomach lining [other wrong options] [Discuss in forum] ![]() ![]() It helps to transport carbon dioxide in the blood It is critical for the biosynthesis of DNA It is a chemical derivative of aspirin |
Q15 ⇒ The cleavage specificity of trypsin and chymotrypsin depend in part on the size, shape, and charge of the active site or specificity pocket [other wrong options] [Discuss in forum] ![]() ![]() proximity of Ser 195 to the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket absence of water in the active site |
Q16 ⇒ The nucleophile in serine proteases is both (a) and (b) [other wrong options] [Discuss in forum] ![]() ![]() Serine water Asparagine |