Home⇒ Medical Science⇒ Biochemistry⇒ Disease associated with immune system
| 1-Dont try to cram or spend more time here just read it fast and cover syllabus then practice MCQ's cheptor of same topic to check your progress. . |
| 2-Wrong options are also given but dont concentrate there, Right answer is in bold format. |
| Q1 ⇒ If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced alternative complement activation. [other wrong options] [Discuss in forum] |
| Q2 ⇒ DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a nude mouse [other wrong options] [Discuss in forum] |
| Q3 ⇒ Retinoblastoma is due to a mutation in a tumor supressor [other wrong options] [Discuss in forum] |
| Q4 ⇒ Bone marrow given to an infant with SCID must come from a donor that shares some MHC alleles with the recipient [other wrong options] [Discuss in forum] |
| Q5 ⇒ Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with macrophage intracellular killing of bacteria [other wrong options] [Discuss in forum] |
| Q6 ⇒ A selective IgA deficiency would be expected to result in problems with mucosal pathogens [other wrong options] [Discuss in forum] |
| Q7 ⇒ An autoimmune disease is Lupus [other wrong options] [Discuss in forum] |
| Q8 ⇒ X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be failure of Th2 cells to provide co-stimulation for B cell isotype switching [other wrong options] [Discuss in forum] |
| Q9 ⇒ To treat HIV infections using drugs, the major problem is that the virus particles with altered (mutant) proteases arise [other wrong options] [Discuss in forum] |
| Q10 ⇒ Infants are most susceptible to bacterial infection due to low circulating levels of IgG at 3-12 months of age [other wrong options] [Discuss in forum] |
| Q11 ⇒ A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind Tyr or Phe [other wrong options] [Discuss in forum] |
| Q12 ⇒ An example of an immunodeficiency disorder is AIDS [other wrong options] [Discuss in forum] |
| Q13 ⇒ Specific translocations are associated with some leukemias [other wrong options] [Discuss in forum] |
| Q14 ⇒ The primary reason for AIDS, a deadly disease is that it destroys key components of the body's internal defense system [other wrong options] [Discuss in forum] |
| Q15 ⇒ Which of the Rous sarcoma virus has a homologous cellular protein? c-src [other wrong options] [Discuss in forum] |
| Q16 ⇒ Difficulties with somatic gene therapy arise from all of the following except GVHD caused by mature T cells in the transplanted cells [other wrong options] [Discuss in forum] |
| Q17 ⇒ Combined cellular and humoral immune deficiencies result from lack of all of the following except transporter of antigen peptides (TAP) [other wrong options] [Discuss in forum] |
| Q18 ⇒ The HIV virus infects primarily cells in the immune system [other wrong options] [Discuss in forum] |
| Q19 ⇒ The chemical, typically released by the body in an allergic response is histamine [other wrong options] [Discuss in forum] |